Human POLE3 protein (Recombinant) (N-His) (STJP016184)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human POLE3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | POLE3 |
| Gene ID | 54107 |
| Uniprot ID | DPOE3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn147 |
Additional Info
| Function | Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication. Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex. |
| Protein Name | Dna Polymerase Epsilon Subunit 3Arsenic-Transactivated ProteinAstpChromatin Accessibility Complex 17 Kda ProteinChrac-17Huchrac17Dna Polymerase Ii Subunit 3Dna Polymerase Epsilon Subunit P17 |
| Database Links | Reactome: R-HSA-110314Reactome: R-HSA-5651801Reactome: R-HSA-5656169Reactome: R-HSA-5685942Reactome: R-HSA-5696397Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-68952Reactome: R-HSA-68962 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dna Polymerase Epsilon Subunit 3 proteinArsenic-Transactivated Protein proteinAstp proteinChromatin Accessibility Complex 17 Kda Protein proteinChrac-17 proteinHuchrac17 proteinDna Polymerase Ii Subunit 3 proteinDna Polymerase Epsilon Subunit P17 proteinPOLE3 proteinCHRAC17 protein |
Information sourced from Uniprot.org