Human PNPLA3 (Patatin Like Phospholipase Domain Containing Protein 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017967)
SPECIFICATIONS
General Information
| Short Description | This PNPLA3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.29ng/mL |
| Detection Limit | 0.781-50ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | PNPLA3 |
| Gene ID | 80339 |
| Uniprot ID | PLPL3_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity. |
| Protein Name | 1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3Acylglycerol TransacylaseAdiponutrinAdpnCalcium-Independent Phospholipase A2-EpsilonIpla2-EpsilonLysophosphatidic Acid AcyltransferasePatatin-Like Phospholipase Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-1482883 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinLipid Droplet |
| Alternative ELISA Names | 1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3 ELISA kitAcylglycerol Transacylase ELISA kitAdiponutrin ELISA kitAdpn ELISA kitCalcium-Independent Phospholipase A2-Epsilon ELISA kitIpla2-Epsilon ELISA kitLysophosphatidic Acid Acyltransferase ELISA kitPatatin-Like Phospholipase Domain-Containing Protein 3 ELISA kitPNPLA3 ELISA kitADPN ELISA kitC22orf20 ELISA kit |
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Information sourced from Uniprot.org