Human PLEC protein (Recombinant) (N-His) (STJP005437)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PLEC-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PLEC |
| Gene ID | 5339 |
| Uniprot ID | PLEC_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp175-Pro400 |
Additional Info
| Post Translational Modifications | Phosphorylated by CDK1.regulates dissociation from intermediate filaments during mitosis. |
| Function | Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity. |
| Protein Name | PlectinPcnPltnHemidesmosomal Protein 1Hd1Plectin-1 |
| Database Links | Reactome: R-HSA-2022090Reactome: R-HSA-264870Reactome: R-HSA-446107 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionHemidesmosomeCell ProjectionPodosomeLocalized To The Cortex Of Myotube Podosomes |
| Alternative Protein Names | Plectin proteinPcn proteinPltn proteinHemidesmosomal Protein 1 proteinHd1 proteinPlectin-1 proteinPLEC proteinPLEC1 protein |
Information sourced from Uniprot.org