Human PLCB1 protein (Recombinant) (N-His) (STJP006062)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PLCB1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PLCB1 |
| Gene ID | 23236 |
| Uniprot ID | PLCB1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys27-Met245 |
Additional Info
| Function | Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. Regulates the function of the endothelial barrier. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1Plc-154Phosphoinositide Phospholipase C-Beta-1Phospholipase C-IPlc-IPhospholipase C-Beta-1Plc-Beta-1 |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-1855204Reactome: R-HSA-399997Reactome: R-HSA-4086398Reactome: R-HSA-416476Reactome: R-HSA-418217Reactome: R-HSA-434316Reactome: R-HSA-500657 |
| Cellular Localisation | Nucleus MembraneCytoplasmColocalizes With The Adrenergic ReceptorsAdren1a And Adren1bAt The Nuclear Membrane Of Cardiac Myocytes |
| Alternative Protein Names | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1 proteinPlc-154 proteinPhosphoinositide Phospholipase C-Beta-1 proteinPhospholipase C-I proteinPlc-I proteinPhospholipase C-Beta-1 proteinPlc-Beta-1 proteinPLCB1 proteinKIAA0581 protein |
Information sourced from Uniprot.org