Human PLB1 protein (Recombinant) (N-His) (STJP005585)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PLB1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PLB1 |
| Gene ID | 151056 |
| Uniprot ID | PLB1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1036-Leu1458 |
Additional Info
| Post Translational Modifications | Undergoes proteolytic cleavage in the ileum. |
| Function | Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border. |
| Protein Name | Phospholipase B1 - Membrane-AssociatedPhospholipase BHplbLysophospholipasePhospholipase A2Phospholipase B/LipasePlb/LipTriacylglycerol Lipase |
| Database Links | Reactome: R-HSA-1482788Reactome: R-HSA-975634 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type I Membrane ProteinPresent In The Intestinal Brush Border Membranes |
| Alternative Protein Names | Phospholipase B1 - Membrane-Associated proteinPhospholipase B proteinHplb proteinLysophospholipase proteinPhospholipase A2 proteinPhospholipase B/Lipase proteinPlb/Lip proteinTriacylglycerol Lipase proteinPLB1 proteinPLB protein |
Information sourced from Uniprot.org