Human PLAA (Phospholipase A2 Activating Protein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017921)
SPECIFICATIONS
General Information
| Short Description | This PLAA Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.114ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | PLAA |
| Gene ID | 9373 |
| Uniprot ID | PLAP_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis. |
| Protein Name | Phospholipase A-2-Activating ProteinPla2pPlap |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmSynapseRecruited To Damaged Lysosomes Decorated With K48-Linked Ubiquitin Chains |
| Alternative ELISA Names | Phospholipase A-2-Activating Protein ELISA kitPla2p ELISA kitPlap ELISA kitPLAA ELISA kitPLAP ELISA kit |
| output |
Information sourced from Uniprot.org