Human PIR protein (Recombinant) (N-His) (STJP010611)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PIR-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PIR |
| Gene ID | 8544 |
| Uniprot ID | PIR_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn290 |
Additional Info
| Function | Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). |
| Protein Name | PirinProbable Quercetin 2 -3-Dioxygenase PirProbable Quercetinase |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | NucleusCytoplasmPredominantly Localized In Dot-Like Subnuclear StructuresCytoplasmic Localization Of Pir Seems To Positively Correlate With Melanoma Progression |
| Alternative Protein Names | Pirin proteinProbable Quercetin 2 -3-Dioxygenase Pir proteinProbable Quercetinase proteinPIR protein |
Information sourced from Uniprot.org