Human PEX19 protein (Recombinant) (N-His) (STJP008942)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PEX19-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PEX19 |
| Gene ID | 5824 |
| Uniprot ID | PEX19_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu98-His263 |
Additional Info
| Function | Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. |
| Protein Name | Peroxisomal Biogenesis Factor 1933 Kda Housekeeping ProteinPeroxin-19Peroxisomal Farnesylated Protein |
| Database Links | Reactome: R-HSA-1369062Reactome: R-HSA-9603798 |
| Cellular Localisation | CytoplasmPeroxisome MembraneLipid-AnchorCytoplasmic SideMainly CytoplasmicSome Fraction Membrane-Associated To The Outer Surface Of Peroxisomes |
| Alternative Protein Names | Peroxisomal Biogenesis Factor 19 protein33 Kda Housekeeping Protein proteinPeroxin-19 proteinPeroxisomal Farnesylated Protein proteinPEX19 proteinHK33 proteinPXF proteinOK proteinSW-cl.22 protein |
Information sourced from Uniprot.org