Human PDGF-BB (Platelet-Derived Growth Factor Subunit B) Antibody Pair (STJAP00465)
General Information
| Short Description | This PDGF-BB antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | PDGFB |
| Gene ID | 5155 |
| Uniprot ID | PDGFB_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human PDGF-BB protien.Detection Immunogen: Recombinant Human PDGF-BB protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
| Protein Name | Platelet-Derived Growth Factor Subunit BPdgf Subunit BPdgf-2Platelet-Derived Growth Factor B ChainPlatelet-Derived Growth Factor Beta PolypeptideProto-Oncogene C-SisBecaplermin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Pair Names | Platelet-Derived Growth Factor Subunit B antibody pairPdgf Subunit B antibody pairPdgf-2 antibody pairPlatelet-Derived Growth Factor B Chain antibody pairPlatelet-Derived Growth Factor Beta Polypeptide antibody pairProto-Oncogene C-Sis antibody pairBecaplermin antibody pairPDGFB antibody pairPDGF2 antibody pairSIS antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human PDGF-BB (Platelet-Derived Growth Factor Subunit B) Antibody Pair (STJAP00465)
This antibody pair detects human PDGF-BB (Platelet-Derived Growth Factor Subunit B, UniProt P01127) and has confirmed reactivity with human samples only. It is not validated for detection of PDGF-BB in other species.
Both antibodies are goat-derived and purified by antigen affinity, each supplied at 0.5 mg/mL. The capture antibody is unconjugated, formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is biotinylated and formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5.
This pair is validated for use in ELISA. No other assay formats are listed as validated applications for this product.
This antibody pair is suitable for use with serum, plasma, and other biological fluids. No additional sample types are specified in the product documentation.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Both the capture and detection antibodies were raised against recombinant human PDGF-BB protein. Both antibodies are goat-derived and purified by antigen affinity chromatography.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.