Human PDE6D protein (Recombinant) (C-Fc) (STJP010134)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PDE6D-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PDE6D |
| Gene ID | 5147 |
| Uniprot ID | PDE6D_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Val150 |
Additional Info
| Function | Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Required for RAB28 localization to the cone cell outer segments in the retina. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate. |
| Protein Name | Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit DeltaGmp-Pde DeltaProtein P17 |
| Database Links | Reactome: R-HSA-5624958Reactome: R-HSA-9648002 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoskeletonCilium Basal Body |
| Alternative Protein Names | Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta proteinGmp-Pde Delta proteinProtein P17 proteinPDE6D proteinPDED protein |
Information sourced from Uniprot.org