Human PAPSS2 protein (Recombinant) (N-His) (STJP016362)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PAPSS2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | PAPSS2 |
| Gene ID | 9060 |
| Uniprot ID | PAPS2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu231-Asn614 |
Additional Info
| Function | Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth. |
| Protein Name | Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2Paps Synthase 2Papss 2Sulfurylase Kinase 2Sk 2Sk2 Includes - Sulfate AdenylyltransferaseAtp-SulfurylaseSulfate Adenylate TransferaseSat - Adenylyl-Sulfate Kinase3'-Phosphoadenosine-5'-Phosphosulfate SynthaseAps KinaseAdenosine-5'-Phosphosulfate 3'-PhosphotransferaseAdenylylsulfate 3'-Phosphotransferase |
| Database Links | Reactome: R-HSA-174362Reactome: R-HSA-2408550Reactome: R-HSA-3560796 |
| Cellular Localisation | |
| Alternative Protein Names | Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 proteinPaps Synthase 2 proteinPapss 2 proteinSulfurylase Kinase 2 proteinSk 2 proteinSk2 Includes - Sulfate Adenylyltransferase proteinAtp-Sulfurylase proteinSulfate Adenylate Transferase proteinSat - Adenylyl-Sulfate Kinase protein3'-Phosphoadenosine-5'-Phosphosulfate Synthase proteinAps Kinase proteinAdenosine-5'-Phosphosulfate 3'-Phosphotransferase proteinAdenylylsulfate 3'-Phosphotransferase proteinPAPSS2 proteinATPSK2 protein |
Information sourced from Uniprot.org