Human PAOX (Polyamine Oxidase) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017656)
SPECIFICATIONS
General Information
| Short Description | This PAOX Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 31.5pg/mL |
| Detection Limit | 78.1-5000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | PAOX |
| Gene ID | 196743 |
| Uniprot ID | PAOX_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. |
| Post Translational Modifications | |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
| Protein Name | Peroxisomal N(1-Acetyl-Spermine/Spermidine OxidasePolyamine Oxidase |
| Database Links | Reactome: R-HSA-141334Reactome: R-HSA-351200Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeCytoplasm |
| Alternative ELISA Names | Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase ELISA kitPolyamine Oxidase ELISA kitPAOX ELISA kitPAO ELISA kitUNQ1923 ELISA kitPRO4398 ELISA kit |
| output |
Information sourced from Uniprot.org