| Tissue Specificity | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. |
| Post Translational Modifications | |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
| Protein Name | Peroxisomal N(1-Acetyl-Spermine/Spermidine OxidasePolyamine Oxidase |
| Database Links | Reactome: R-HSA-141334Reactome: R-HSA-351200Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeCytoplasm |
| Alternative ELISA Names | Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase ELISA kitPolyamine Oxidase ELISA kitPAOX ELISA kitPAO ELISA kitUNQ1923 ELISA kitPRO4398 ELISA kit |
| output | |
Information sourced from Uniprot.org
