Human OSMR (Oncostatin-M-specific receptor subunit beta) CLIA Kit for Quantitative Detection

Name: Human OSMR (Oncostatin-M-specific receptor subunit beta) CLIA Kit for Quantitative Detection
SKU: STJC0000940
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJC0000940

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Short Description	This human OSMR kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications	CLIA
Reactivity	Human
Sensitivity	18.75pg/mL
Detection Limit	31.25~2000pg/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Chemiluminescence

Gene Symbol	OSMR
Gene ID	9180
Uniprot ID	OSMR_HUMAN
Specificity	This kit recognizes Human OSMR in samples. No significant cross-reactivity or interference between Human OSMR and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Tissue Specificity	Expressed in keratinocytes (at protein level). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells.
Function	Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Protein Name	Oncostatin-M-Specific Receptor Subunit Beta Interleukin-31 Receptor Subunit Beta Il-31 Receptor Subunit Beta Il-31r Subunit Beta Il-31r-Beta Il-31rb
Database Links	Reactome: R-HSA-6788467
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative CLIA Names	Oncostatin-M-Specific Receptor Subunit Beta CLIA kit Interleukin-31 Receptor Subunit Beta CLIA kit Il-31 Receptor Subunit Beta CLIA kit Il-31r Subunit Beta CLIA kit Il-31r-Beta CLIA kit Il-31rb CLIA kit OSMR CLIA kit OSMRB CLIA kit
Specificity	This kit recognizes Human OSMR in samples. No significant cross-reactivity or interference between Human OSMR and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	104.61	243.26	725.40	105.97	257.71	754.98
Standard deviation	10.54	28.17	61.08	11.01	28.81	53.68
CV (%)	10.08	11.58	8.42	10.39	11.18	7.11