Human OSBPL2 protein (Recombinant) (N-His) (STJP008391)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human OSBPL2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | OSBPL2 |
| Gene ID | 9885 |
| Uniprot ID | OSBL2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala96-Asp325 |
Additional Info
| Function | Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro). |
| Protein Name | Oxysterol-Binding Protein-Related Protein 2Orp-2Osbp-Related Protein 2 |
| Database Links | Reactome: R-HSA-192105 |
| Cellular Localisation | CytoplasmCytosolLipid DropletCell MembranePeripheral Membrane ProteinCytoplasmic SideDetected On The Surface Of Cytosolic Lipid DropletsRecruited To The Cell Membrane By Phosphatidylinositol-Phosphate Binding |
| Alternative Protein Names | Oxysterol-Binding Protein-Related Protein 2 proteinOrp-2 proteinOsbp-Related Protein 2 proteinOSBPL2 proteinKIAA0772 proteinORP2 protein |
Information sourced from Uniprot.org