Human OLFM4 (OLFM4) Antibody Pair (STJAP00898)
General Information
| Short Description | This OLFM4 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R03-8H-9/R09-1D-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | OLFM4 |
| Gene ID | 10562 |
| Uniprot ID | OLFM4_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Expressed during myeloid lineage development. Much higher expression in bone marrow neutrophils than in peripheral blood neutrophils (at protein level). Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Overexpressed in some pancreatic cancer tissues. |
| Post Translational Modifications | N-glycosylated. |
| Function | May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. |
| Protein Name | Olfactomedin-4Olm4Antiapoptotic Protein Gw112G-Csf-Stimulated Clone 1 ProteinHgc-1Holfd |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedExtracellular SpaceMitochondrionSubcellular Location Is Not Clearly Defined: Has Been Shown To Be SecretedBut Also In The MitochondrionCytoplasm And Plasma Membrane And In The Nucleus |
| Alternative Antibody Pair Names | Olfactomedin-4 antibody pairOlm4 antibody pairAntiapoptotic Protein Gw112 antibody pairG-Csf-Stimulated Clone 1 Protein antibody pairHgc-1 antibody pairHolfd antibody pairOLFM4 antibody pairGW112 antibody pairUNQ362 antibody pairPRO698 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human OLFM4 (OLFM4) Antibody Pair (STJAP00898)
This antibody pair is designed to detect human OLFM4 (Olfactomedin-4, UniProt Q6UX06) and has confirmed reactivity with human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated and purified by affinity chromatography. They are formulated in 0.01M PBS at pH 7.2. The user is responsible for determining which clone to assign as capture or detection and for any labeling required for the detection antibody.
This pair is validated for use in ELISA. No other assay formats are listed in the product specifications.
The two monoclonal antibodies are identified by clone IDs R03-8H-9 and R09-1D-5, both raised in rabbit against a recombinant OLFM4 protein immunogen.
Optimal working concentrations are not predefined in the product specifications and must be determined empirically by the end user for their specific experimental conditions.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, they should be aliquoted and kept at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.