Human ODC1 protein (Recombinant) (His-Tag) (STJP017378)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ODC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ODC1 |
| Gene ID | 4953 |
| Uniprot ID | DCOR_HUMAN |
| Accession Number | NP_002530 |
| Immunogen | Human |
| Immunogen Region | 1-461aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. |
| Function | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. |
| Protein Name | Ornithine DecarboxylaseOdc |
| Database Links | Reactome: R-HSA-350562Reactome: R-HSA-351202 |
| Cellular Localisation | |
| Alternative Protein Names | Ornithine Decarboxylase proteinOdc proteinODC1 protein |
Information sourced from Uniprot.org