Human NUDT7 protein (Recombinant) (N-His) (STJP010845)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NUDT7-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NUDT7 |
| Gene ID | 283927 |
| Uniprot ID | NUDT7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu238 |
Additional Info
| Function | Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. Exhibits decapping activity towards dpCoA-capped RNAs in vitro. |
| Protein Name | Peroxisomal Coenzyme A Diphosphatase Nudt7Nucleoside Diphosphate-Linked Moiety X Motif 7Nudix Motif 7 |
| Database Links | Reactome: R-HSA-390918Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Protein Names | Peroxisomal Coenzyme A Diphosphatase Nudt7 proteinNucleoside Diphosphate-Linked Moiety X Motif 7 proteinNudix Motif 7 proteinNUDT7 protein |
Information sourced from Uniprot.org