Human NUDT10 protein (Recombinant) (His-Tag) (STJP017165)

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STJP017165
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Short Description :Recombinant-Human NUDT10-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:NUDT10
Gene ID:170685
Uniprot ID:NUD10_HUMAN
Accession Number:NP_694853
Immunogen:Human
Immunogen Region:1-164aa
Immunogen Sequence:MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDP
Tissue Specificity Mainly expressed in testis and, at lower level in brain. it is widely expressed.
Function Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Protein Name Diphosphoinositol Polyphosphate Phosphohydrolase 3-Alpha
Dipp-3-Alpha
Dipp3-Alpha
Hdipp3alpha
Diadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-Alpha
Diadenosine Hexaphosphate Hydrolase
Amp-Forming
Nucleoside Diphosphate-Linked Moiety X Motif 10
Nudix Motif 10
Haps2
Database Links Reactome: R-HSA-1855167
Cellular Localisation Cytoplasm
Alternative Protein Names Diphosphoinositol Polyphosphate Phosphohydrolase 3-Alpha protein
Dipp-3-Alpha protein
Dipp3-Alpha protein
Hdipp3alpha protein
Diadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-Alpha protein
Diadenosine Hexaphosphate Hydrolase protein
Amp-Forming protein
Nucleoside Diphosphate-Linked Moiety X Motif 10 protein
Nudix Motif 10 protein
Haps2 protein
NUDT10 protein
APS2 protein
DIPP3A protein

Information sourced from Uniprot.org