| Tissue Specificity | Mainly expressed in testis and, at lower level in brain. it is widely expressed. |
| Function | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. |
| Protein Name | Diphosphoinositol Polyphosphate Phosphohydrolase 3-AlphaDipp-3-AlphaDipp3-AlphaHdipp3alphaDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-AlphaDiadenosine Hexaphosphate HydrolaseAmp-FormingNucleoside Diphosphate-Linked Moiety X Motif 10Nudix Motif 10Haps2 |
| Database Links | Reactome: R-HSA-1855167 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Diphosphoinositol Polyphosphate Phosphohydrolase 3-Alpha proteinDipp-3-Alpha proteinDipp3-Alpha proteinHdipp3alpha proteinDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-Alpha proteinDiadenosine Hexaphosphate Hydrolase proteinAmp-Forming proteinNucleoside Diphosphate-Linked Moiety X Motif 10 proteinNudix Motif 10 proteinHaps2 proteinNUDT10 proteinAPS2 proteinDIPP3A protein |
Information sourced from Uniprot.org