Human ACOT13 protein (Recombinant) (His-Tag) (STJP016871)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ACOT13-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACOT13 |
| Gene ID | 55856 |
| Uniprot ID | ACO13_HUMAN |
| Accession Number | NP_060943 |
| Immunogen | Human |
| Immunogen Region | 1-140aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis. |
| Protein Name | Acyl-Coenzyme A Thioesterase 13Acyl-Coa Thioesterase 13Hotdog-Fold Thioesterase Superfamily Member 2Palmitoyl-Coa HydrolaseThioesterase Superfamily Member 2Them2 Cleaved Into - Acyl-Coenzyme A Thioesterase 13 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | CytoplasmCytosolMitochondrionNucleusCytoskeletonSpindleDuring InterphaseFound Both In The Nucleus And In The CytoplasmAt MitosisLocalizes To The SpindleColocalizes With Tubulin |
| Alternative Protein Names | Acyl-Coenzyme A Thioesterase 13 proteinAcyl-Coa Thioesterase 13 proteinHotdog-Fold Thioesterase Superfamily Member 2 proteinPalmitoyl-Coa Hydrolase proteinThioesterase Superfamily Member 2 proteinThem2 Cleaved Into - Acyl-Coenzyme A Thioesterase 13 - N-Terminally Processed proteinACOT13 proteinTHEM2 proteinHT012 proteinPNAS-27 protein |
Information sourced from Uniprot.org