Human NUDT10 protein (Recombinant) (His-Tag) (STJP017165)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human NUDT10-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUDT10 |
| Gene ID | 170685 |
| Uniprot ID | NUD10_HUMAN |
| Accession Number | NP_694853 |
| Immunogen | Human |
| Immunogen Region | 1-164aa |
| Immunogen Sequence | MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDP |
Additional Info
| Tissue Specificity | Mainly expressed in testis and, at lower level in brain. it is widely expressed. |
| Function | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. |
| Protein Name | Diphosphoinositol Polyphosphate Phosphohydrolase 3-AlphaDipp-3-AlphaDipp3-AlphaHdipp3alphaDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-AlphaDiadenosine Hexaphosphate HydrolaseAmp-FormingNucleoside Diphosphate-Linked Moiety X Motif 10Nudix Motif 10Haps2 |
| Database Links | Reactome: R-HSA-1855167 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Diphosphoinositol Polyphosphate Phosphohydrolase 3-Alpha proteinDipp-3-Alpha proteinDipp3-Alpha proteinHdipp3alpha proteinDiadenosine 5' -5'''-P1 -P6-Hexaphosphate Hydrolase 3-Alpha proteinDiadenosine Hexaphosphate Hydrolase proteinAmp-Forming proteinNucleoside Diphosphate-Linked Moiety X Motif 10 proteinNudix Motif 10 proteinHaps2 proteinNUDT10 proteinAPS2 proteinDIPP3A protein |
Information sourced from Uniprot.org