Human NUCB2 (Nucleobindin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017528)
SPECIFICATIONS
General Information
| Short Description | This NUCB2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 13.8pg/mL |
| Detection Limit | 31.2-2000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | NUCB2 |
| Gene ID | 4925 |
| Uniprot ID | NUCB2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Predominantly expressed in spleen, testis and normal stomach. |
| Post Translational Modifications | |
| Function | Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. In intestinal epithelial cells, plays a role in the inhibition of hepatic glucose production via MC4R receptor leading to increased cyclic adenosine monophosphate (cAMP) levels and glucagon-like peptide 1 (GLP-1) secretion. |
| Protein Name | Nucleobindin-2Dna-Binding Protein NefaEpididymis Secretory Protein Li 109Gastric Cancer Antigen Zg4Prepronesfatin Cleaved Into - Nesfatin-1 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusMembranePeripheral Membrane ProteinCytoplasmSecretedEndoplasmic ReticulumNucleus EnvelopeGolgi Retention Is Mediated By Its N-Terminal RegionNesfatin-1: Secreted |
| Alternative ELISA Names | Nucleobindin-2 ELISA kitDna-Binding Protein Nefa ELISA kitEpididymis Secretory Protein Li 109 ELISA kitGastric Cancer Antigen Zg4 ELISA kitPrepronesfatin Cleaved Into - Nesfatin-1 ELISA kitNUCB2 ELISA kitNEFA ELISA kit |
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Information sourced from Uniprot.org