Human NUBP2 protein (Recombinant) (His-Tag) (STJP018985)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human NUBP2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 50% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUBP2 |
| Gene ID | 10101 |
| Uniprot ID | NUBP2_HUMAN |
| Accession Number | NP_036357 |
| Immunogen | Human |
| Immunogen Region | 1-271aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEAAAEP GNLAGVRHII LVLSGKGGVG KSTISTELAL ALRHAGKKVG ILDVDLCGPS IPRMLGAQGR AVHQCDRGWA PVFLDREQSI SLMSVGFLLE KPDEAVVWRG PKKNALIKQF VSDVAWGELD YLVVDTPPGT SDEHMATIEA LRPYQPLGAL VVTTPQAVSV GDVRRELTFC RKTGLRVMGI VENMSGFTCP HCTECTSV |
Additional Info
| Tissue Specificity | Widely expressed with highest expression in skeletal muscle. |
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. |
| Protein Name | Cytosolic Fe-S Cluster Assembly Factor Nubp2Nucleotide-Binding Protein 2Nbp 2 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium AxonemeCentrioleEnriched At The Centrosomes During MitosisEnriched In Centrioles Of Microtubule Asters During ProphasePrometaphase And Telophase Stages Of MitosisLocalized At Centrioles And In The Nucleus At InterphaseColocalizes With Nubp-1 At Prometaphase |
| Alternative Protein Names | Cytosolic Fe-S Cluster Assembly Factor Nubp2 proteinNucleotide-Binding Protein 2 proteinNbp 2 proteinNUBP2 protein |
Information sourced from Uniprot.org