Human NT5M protein (Recombinant) (His-Tag) (STJP017294)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human NT5M-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NT5M |
| Gene ID | 56953 |
| Uniprot ID | NT5M_HUMAN |
| Accession Number | NP_064586.1 |
| Immunogen | Human |
| Immunogen Region | 32-228aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas. |
| Function | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. |
| Protein Name | 5'(3'-Deoxyribonucleotidase - Mitochondrial5' -3'-Nucleotidase - MitochondrialDeoxy-5'-Nucleotidase 2Dnt-2 |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | 5'(3'-Deoxyribonucleotidase - Mitochondrial protein5' -3'-Nucleotidase - Mitochondrial proteinDeoxy-5'-Nucleotidase 2 proteinDnt-2 proteinNT5M proteinDNT2 protein |
Information sourced from Uniprot.org