Human NT5C2 protein (Recombinant) (His-Tag) (STJP017355)

Name: Human NT5C2 protein (Recombinant) (His-Tag) (STJP017355)
SKU: STJP017355
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017355

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Short Description	Recombinant-Human NT5C2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	NT5C2
Gene ID	22978
Uniprot ID	5NTC_HUMAN
Accession Number	NP_036361.1
Immunogen	Human
Immunogen Region	1-561aa
Immunogen Sequence	MSTSWSDRLQ NAADMPANMD KHALKKYRRE AYHRVFVNRS LAMEKIKCFG FDMDYTLAVY KSPEYESLGF ELTVERLVSI GYPQELLSFA YDSTFPTRGL VFDTLYGNLL KVDAYGNLLV CAHGFNFIRG PETREQYPNK FIQRDDTERF YILNTLFNLP ETYLLACLVD FFTNCPRYTS CETGFKDGDL FMSYRSMFQD VRDAVD

Tissue Specificity	Widely expressed.
Function	Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell.
Protein Name	Cytosolic Purine 5'-Nucleotidase Cytosolic 5'-Nucleotidase Ii Cn-Ii Cytosolic Imp/Gmp-Specific 5'-Nucleotidase Cytosolic Nucleoside Phosphotransferase 5'N High Km 5'-Nucleotidase
Database Links	Reactome: R-HSA-2161541 Reactome: R-HSA-74259 Reactome: R-HSA-9755088
Cellular Localisation	Cytoplasm Cytosol
Alternative Protein Names	Cytosolic Purine 5'-Nucleotidase protein Cytosolic 5'-Nucleotidase Ii protein Cn-Ii protein Cytosolic Imp/Gmp-Specific 5'-Nucleotidase protein Cytosolic Nucleoside Phosphotransferase 5'N protein High Km 5'-Nucleotidase protein NT5C2 protein NT5B protein NT5CP protein PNT5 protein

Information sourced from Uniprot.org