Human NPPC protein (Recombinant) (N-His-SUMO) (STJP009606)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NPPC-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NPPC |
| Gene ID | 4880 |
| Uniprot ID | ANFC_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly61-Cys126 |
Additional Info
| Post Translational Modifications | CNP-22: Degraded by IDE (in vitro). |
| Function | CNP-22: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3. |
| Protein Name | C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-Type Natriuretic Peptide Cleaved Into - Cnp-22 - Cnp-29 - Cnp-53 proteinNPPC proteinCNP2 protein |
Information sourced from Uniprot.org