Human NOS1 protein (Recombinant) (N-His) (STJP004504)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP004504
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General Information

Short DescriptionRecombinant-Human NOS1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolNOS1
Gene ID4842
Uniprot IDNOS1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionVal1193-Asn1393

Additional Info

Post Translational Modifications Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Protein Name Nitric Oxide Synthase 1
Constitutive Nos
Nc-Nos
Nos Type I
Neuronal Nos
N-Nos
Nnos
Nitric Oxide Synthase - Brain
Bnos
Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-392154
Reactome: R-HSA-5578775
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cell Projection
Dendritic Spine
In Skeletal Muscle
It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex
In Neurons
Enriched In Dendritic Spines
Alternative Protein Names Nitric Oxide Synthase 1 protein
Constitutive Nos protein
Nc-Nos protein
Nos Type I protein
Neuronal Nos protein
N-Nos protein
Nnos protein
Nitric Oxide Synthase - Brain protein
Bnos protein
Peptidyl-Cysteine S-Nitrosylase Nos1 protein
NOS1 protein

Information sourced from Uniprot.org

Citations

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