Human NOS1 protein (Recombinant) (N-His) (STJP004504)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NOS1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NOS1 |
| Gene ID | 4842 |
| Uniprot ID | NOS1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val1193-Asn1393 |
Additional Info
| Post Translational Modifications | Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro). |
| Function | Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. |
| Protein Name | Nitric Oxide Synthase 1Constitutive NosNc-NosNos Type INeuronal NosN-NosNnosNitric Oxide Synthase - BrainBnosPeptidyl-Cysteine S-Nitrosylase Nos1 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-392154Reactome: R-HSA-5578775 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCell ProjectionDendritic SpineIn Skeletal MuscleIt Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein ComplexIn NeuronsEnriched In Dendritic Spines |
| Alternative Protein Names | Nitric Oxide Synthase 1 proteinConstitutive Nos proteinNc-Nos proteinNos Type I proteinNeuronal Nos proteinN-Nos proteinNnos proteinNitric Oxide Synthase - Brain proteinBnos proteinPeptidyl-Cysteine S-Nitrosylase Nos1 proteinNOS1 protein |
Information sourced from Uniprot.org