Human NKX6-1 (NK6 Homeobox Protein 1) Sandwich ELISA Kit (STJE0010982)
SPECIFICATIONS
General Information
| Short Description | This NKX6-1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.096ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | NKX6-1 |
| Gene ID | 4825 |
| Uniprot ID | NKX61_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Pancreatic beta cells. |
| Post Translational Modifications | |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Homeobox Protein Nkx-6.1 ELISA kitHomeobox Protein Nk-6 Homolog A ELISA kitNKX6-1 ELISA kitNKX6A ELISA kit |
| output |
Information sourced from Uniprot.org