Human NKp30/NCR3 (Natural cytotoxicity triggering receptor 3) Sandwich ELISA Kit (STJE0020119)
SPECIFICATIONS
General Information
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 9.375 pg/mL |
| Detection Limit | 15.625-1000 pg/mL |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Storage Instruction | Store unopened box at 2-8 °C for up to 1 month. For longer storage check individual components. |
| Assay Time | 4 hours |
Target Information
| Gene Symbol | NCR3 |
| Gene ID | 259197 |
| Uniprot ID | NCTR3_HUMAN |
| Specificity | This Sandwich ELISA kit recognizes Human Natural cytotoxicity triggering receptor 3 in various sample types. No significant cross-reactivity or interference was observed between Human NKp30/NCR3 analogues. |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Additional Info
| Tissue Specificity | Selectively expressed by all resting and activated NK cells and weakly expressed in spleen. |
| Post Translational Modifications | |
| Function | Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 3Activating Natural Killer Receptor P30Natural Killer Cell P30-Related ProteinNk-P30Nkp30Cd Antigen Cd337 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Natural Cytotoxicity Triggering Receptor 3 ELISA kitActivating Natural Killer Receptor P30 ELISA kitNatural Killer Cell P30-Related Protein ELISA kitNk-P30 ELISA kitNkp30 ELISA kitCd Antigen Cd337 ELISA kitNCR3 ELISA kit1C7 ELISA kitLY117 ELISA kit |
| output |
Information sourced from Uniprot.org