Human NKG7 protein (Recombinant) (N-GST & C-His) (STJP015896)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NKG7-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | NKG7 |
| Gene ID | 4818 |
| Uniprot ID | NKG7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe29-Phe61 |
Additional Info
| Function | Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases. Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection. Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules. Contributes to NK cell-mediated control of cancer metastasis. |
| Protein Name | Protein Nkg7G-Csf-Induced Gene 1 ProteinGig-1 ProteinGranule Membrane Protein Of 17 KdaGmp-17Natural Killer Cell Protein 7P15-Tia-1 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytolytic Granule Membrane |
| Alternative Protein Names | Protein Nkg7 proteinG-Csf-Induced Gene 1 Protein proteinGig-1 Protein proteinGranule Membrane Protein Of 17 Kda proteinGmp-17 proteinNatural Killer Cell Protein 7 proteinP15-Tia-1 proteinNKG7 proteinGIG1 protein |
Information sourced from Uniprot.org