Human NHE3 (Sodium/Hydrogen Exchanger 3) Sandwich ELISA Kit (STJE0010968)

Human NHE3 (Sodium/Hydrogen Exchanger 3) Sandwich ELISA Kit (STJE0010968)

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STJE0010968
$581.67 - $809.37
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Short Description :This NHE3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.093ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:SLC9A3
Gene ID:6550
Uniprot ID:SL9A3_HUMAN
Sample Type:tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated by PKA, which inhibits activity. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. Phosphorylation at Ser-718 by CSNK2A1 regulates SLC9A3 activity through the formation of multiple signaling complexes.
Function Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation.
Protein Name Sodium/Hydrogen Exchanger 3
Na(+/H(+ Exchanger 3
Nhe-3
Solute Carrier Family 9 Member 3
Database Links Reactome: R-HSA-425986
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Recycling Endosome Membrane
Early Endosome Membrane
In Intestinal Epithelial Cells
Localizes To The Ileal Brush Border
Phosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell Membrane
Angiotensin-2 Enhances Apical Expression
Alternative ELISA Names Sodium/Hydrogen Exchanger 3 ELISA kit
Na(+/H(+ Exchanger 3 ELISA kit
Nhe-3 ELISA kit
Solute Carrier Family 9 Member 3 ELISA kit
SLC9A3 ELISA kit
NHE3 ELISA kit
output

Information sourced from Uniprot.org

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