This NES1 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Human
Sensitivity
9.38pg/mL
Detection Limit
15.63~1000pg/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Human NES1 in samples. No significant cross-reactivity or interference between Human NES1 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Function
Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. In intestinal epithelial cells, plays a role in the inhibition of hepatic glucose production via MC4R receptor leading to increased cyclic adenosine monophosphate (cAMP) levels and glucagon-like peptide 1 (GLP-1) secretion.
Protein Name
Nucleobindin-2Dna-Binding Protein NefaEpididymis Secretory Protein Li 109Gastric Cancer Antigen Zg4Prepronesfatin Cleaved Into - Nesfatin-1
Database Links
Cellular Localisation
Golgi ApparatusMembranePeripheral Membrane ProteinCytoplasmSecretedEndoplasmic ReticulumNucleus EnvelopeGolgi Retention Is Mediated By Its N-Terminal RegionNesfatin-1: Secreted
Alternative ELISA Names
Nucleobindin-2 ELISA kitDna-Binding Protein Nefa ELISA kitEpididymis Secretory Protein Li 109 ELISA kitGastric Cancer Antigen Zg4 ELISA kitPrepronesfatin Cleaved Into - Nesfatin-1 ELISA kitNUCB2 ELISA kitNEFA ELISA kit
Specificity
This kit recognizes Human NES1 in samples. No significant cross-reactivity or interference between Human NES1 and analogues was observed.
