Human NELL2 (NEL Like Protein 2) Sandwich ELISA Kit (STJE0010914)
SPECIFICATIONS
General Information
| Short Description | This NELL2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.113ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | NELL2 |
| Gene ID | 4753 |
| Uniprot ID | NELL2_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Plays multiple roles in neural tissues, regulates neuronal proliferation, survival, differentiation, polarization, as well as axon guidance and synaptic functions. Plays an important role in axon development during neuronal differentiation through the MAPK intracellular signaling pathway. Via binding to its receptor ROBO3, plays a role in axon guidance, functioning as a repulsive axon guidance cue that contributes to commissural axon guidance to the midline. Required for neuron survival through the modulation of MAPK signaling pathways too. Involved in the regulation of hypothalamic GNRH secretion and the control of puberty. Epididymal-secreted protein that signals through a ROS1-pathway to regulate the epididymal initial segment (IS) maturation, sperm maturation and male fertility. |
| Protein Name | Protein Kinase C-Binding Protein Nell2Nel-Like Protein 2Nel-Related Protein 2 |
| Database Links | Reactome: R-HSA-428542 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Protein Kinase C-Binding Protein Nell2 ELISA kitNel-Like Protein 2 ELISA kitNel-Related Protein 2 ELISA kitNELL2 ELISA kitNRP2 ELISA kit |
| output |
Information sourced from Uniprot.org