Human NECTIN4/PVRL4 protein (Recombinant) (C-Fc) (STJP010123)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NECTIN4/PVRL4-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NECTIN4 |
| Gene ID | 81607 |
| Uniprot ID | NECT4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly32-Arg144 |
Additional Info
| Post Translational Modifications | The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE. |
| Function | Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus. |
| Protein Name | Nectin-4Ig Superfamily Receptor LnirNectin Cell Adhesion Molecule 4Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionAdherens JunctionColocalizes With Afdn At Cadherin-Based Adherens JunctionsProcessed Poliovirus Receptor-Related Protein 4: SecretedThe Secreted Form Is Found In Breast Tumor Patients |
| Alternative Protein Names | Nectin-4 proteinIg Superfamily Receptor Lnir proteinNectin Cell Adhesion Molecule 4 proteinPoliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 proteinNECTIN4 proteinLNIR proteinPRR4 proteinPVRL4 protein |
Information sourced from Uniprot.org