Human NDUFA13 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP008188)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NDUFA13-N-His-SUMO & C-Strep protein was developed from e.coli for the region N-His-SUMO & C-Strep. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NDUFA13 |
| Gene ID | 51079 |
| Uniprot ID | NDUAD_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met51-Thr144 |
Additional Info
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 13Cell Death Regulatory Protein Grim-19Complex I-B16.6Ci-B16.6Gene Associated With Retinoic And Interferon-Induced Mortality 19 ProteinGrim-19Gene Associated With Retinoic And Ifn-Induced Mortality 19 ProteinNadh-Ubiquinone Oxidoreductase B16.6 Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinMatrix SideNucleusLocalizes Mainly In The MitochondrionMay Be Translocated Into The Nucleus Upon Ifn/Ra Treatment |
| Alternative Protein Names | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 13 proteinCell Death Regulatory Protein Grim-19 proteinComplex I-B16.6 proteinCi-B16.6 proteinGene Associated With Retinoic And Interferon-Induced Mortality 19 Protein proteinGrim-19 proteinGene Associated With Retinoic And Ifn-Induced Mortality 19 Protein proteinNadh-Ubiquinone Oxidoreductase B16.6 Subunit proteinNDUFA13 proteinGRIM19 proteinCDA016 proteinCGI-39 protein |
Information sourced from Uniprot.org