Human NCK2 protein (Recombinant) (His-Tag) (STJP018340)

Name: Human NCK2 protein (Recombinant) (His-Tag) (STJP018340)
SKU: STJP018340
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018340

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Short Description	Recombinant-Human NCK2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	NCK2
Gene ID	8440
Uniprot ID	NCK2_HUMAN
Accession Number	NP_003572
Immunogen	Human
Immunogen Region	1-380aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSMTEEVIV IAKWDYTAQQ DQELDIKKNE RLWLLDDSKT WWRVRNAANR TGYVPSNYVE RKNSLKKGSL VKNLKDTLGL GKTRRKTSAR DASPTPSTDA EYPANGSGAD RIYDLNIPAF VKFAYVAERE DELSLVKGSR VTVMEKCSDG WWRGSYNGQI GWFPSNYVLE EVDEAAAESP SFLSLRKGAS LSNGQGSRVL HVVQTLYP

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Phosphorylated.
Function	Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Protein Name	Cytoplasmic Protein Nck2 Growth Factor Receptor-Bound Protein 4 Nck Adaptor Protein 2 Nck-2 Sh2/Sh3 Adaptor Protein Nck-Beta
Database Links	Reactome: R-HSA-186763 Reactome: R-HSA-373753 Reactome: R-HSA-3928664 Reactome: R-HSA-428540 Reactome: R-HSA-4420097 Reactome: R-HSA-8985801 Reactome: R-HSA-9013420 Reactome: R-HSA-9013424
Cellular Localisation	Cytoplasm Endoplasmic Reticulum
Alternative Protein Names	Cytoplasmic Protein Nck2 protein Growth Factor Receptor-Bound Protein 4 protein Nck Adaptor Protein 2 protein Nck-2 protein Sh2/Sh3 Adaptor Protein Nck-Beta protein NCK2 protein GRB4 protein

Information sourced from Uniprot.org