Human NAXE protein (Recombinant) (N-His) (STJP005715)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NAXE-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NAXE |
| Gene ID | 128240 |
| Uniprot ID | NNRE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly118-Glu282 |
Additional Info
| Post Translational Modifications | Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation. |
| Function | Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. |
| Protein Name | Nad(Ph-Hydrate EpimeraseApolipoprotein A-I-Binding ProteinAi-BpNad(Phx EpimeraseNaxeYjef N-Terminal Domain-Containing Protein 1Yjef_n1 |
| Database Links | Reactome: R-HSA-197264 |
| Cellular Localisation | MitochondrionSecretedIn SpermSecretion Gradually Increases During Capacitation |
| Alternative Protein Names | Nad(Ph-Hydrate Epimerase proteinApolipoprotein A-I-Binding Protein proteinAi-Bp proteinNad(Phx Epimerase proteinNaxe proteinYjef N-Terminal Domain-Containing Protein 1 proteinYjef_n1 proteinNAXE proteinAIBP proteinAPOA1BP proteinYJEFN1 protein |
Information sourced from Uniprot.org