Human MYL12A protein (Recombinant) (His-Tag) (STJP017293)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MYL12A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYL12A |
| Gene ID | 10627 |
| Uniprot ID | ML12A_HUMAN |
| Accession Number | NP_006462 |
| Immunogen | Human |
| Immunogen Region | 1-171aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. |
| Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. |
| Protein Name | Myosin Regulatory Light Chain 12aEpididymis Secretory Protein Li 24Hel-S-24Mlc-2bMyosin RlcMyosin Regulatory Light Chain 2 - NonsarcomericMyosin Regulatory Light Chain Mrlc3 |
| Database Links | Reactome: R-HSA-3928664Reactome: R-HSA-445355 |
| Cellular Localisation | |
| Alternative Protein Names | Myosin Regulatory Light Chain 12a proteinEpididymis Secretory Protein Li 24 proteinHel-S-24 proteinMlc-2b proteinMyosin Rlc proteinMyosin Regulatory Light Chain 2 - Nonsarcomeric proteinMyosin Regulatory Light Chain Mrlc3 proteinMYL12A proteinMLCB proteinMRLC3 proteinRLC protein |
Information sourced from Uniprot.org