Human MYDGF/SF20 protein (Recombinant-Active) (C-His) (STJP012222)

Name: Human MYDGF/SF20 protein (Recombinant-Active) (C-His) (STJP012222)
SKU: STJP012222-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012222-100

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Active-Human MYDGF/SF20-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Measured by its binding ability in a functional ELISA. When recombinant human MYDGF/SF20 is Immobilised at 2 Mu g/mL (100 Mu L/well) , recombinant human P4HB binds with an ED50 of 0.8-4.8 Mu g/mL.

Function	Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Protein Name	Myeloid-Derived Growth Factor Mydgf
Database Links	Reactome: R-HSA-381038
Cellular Localisation	Secreted Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum Golgi Apparatus The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Protein Names	Myeloid-Derived Growth Factor protein Mydgf protein MYDGF protein C19orf10 protein

Information sourced from Uniprot.org