Human MTO1 protein (Recombinant) (N-His) (STJP016244)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MTO1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | MTO1 |
| Gene ID | 25821 |
| Uniprot ID | MTO1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala518-Thr675 |
Additional Info
| Function | Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity. |
| Protein Name | 5-Taurinomethyluridine-Trna Synthase Subunit Mto1 - MitochondrialMitochondrial Trna Translation Optimization 1Protein Mto1 Homolog - Mitochondrial |
| Database Links | Reactome: R-HSA-6787450 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | 5-Taurinomethyluridine-Trna Synthase Subunit Mto1 - Mitochondrial proteinMitochondrial Trna Translation Optimization 1 proteinProtein Mto1 Homolog - Mitochondrial proteinMTO1 proteinCGI-02 protein |
Information sourced from Uniprot.org