Human MTHFS protein (Recombinant) (His-Tag) (STJP017113)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MTHFS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 30% Glycerol, 0.2M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTHFS |
| Gene ID | 10588 |
| Uniprot ID | MTHFS_HUMAN |
| Accession Number | NP_006432 |
| Immunogen | Human |
| Immunogen Region | 1-203aa |
| Immunogen Sequence |
Additional Info
| Function | Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate. |
| Protein Name | 5-Formyltetrahydrofolate Cyclo-Ligase5 -10-Methenyl-Tetrahydrofolate SynthetaseMthfsMethenyl-Thf Synthetase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | 5-Formyltetrahydrofolate Cyclo-Ligase protein5 -10-Methenyl-Tetrahydrofolate Synthetase proteinMthfs proteinMethenyl-Thf Synthetase proteinMTHFS protein |
Information sourced from Uniprot.org