Function | Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene.this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. |
Protein Name | Transcription Termination Factor 1 - MitochondrialMitochondrial Transcription Termination Factor 1MterfMterf1 |
Database Links | Reactome: R-HSA-163316Reactome: R-HSA-2151201 |
Cellular Localisation | Mitochondrion |
Alternative Protein Names | Transcription Termination Factor 1 - Mitochondrial proteinMitochondrial Transcription Termination Factor 1 proteinMterf proteinMterf1 proteinMTERF1 proteinMTERF protein |
Information sourced from Uniprot.org