Human MSR1/CD204 protein (Recombinant) (C-His) (STJP001113)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human MSR1/CD204 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys77-Leu451) of human CD204 (Accession #NP_619729.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human MSR1/CD204-C-His protein was developed in hek293 cells using the region Lys77-Leu451. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | 1.Measured by its binding ability in a functional ELISA.Immobilized Human MSR1 Protein at 1 Mu g/mL (100 Mu L/well) can bind MSR1 Rabbit pAb with a linear range of 0.76-2.88 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | MSR1 |
| Gene ID | 4481 |
| Uniprot ID | MSRE_HUMAN |
| Immunogen | Recombinant Human MSR1/CD204 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys77-Leu451) of human CD204 (Accession #NP_619729.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Lys77-Leu451 |
| Immunogen Sequence | KWETKNCSVSSTNANDITQS LTGKGNDSEEEMRFQEVFME HMSNMEKRIQHILDMEANLM DTEHFQNFSMTTDQRFNDIL LQLSTLFSSVQGHGNAIDEI SKSLISLNTTLLDLQLNIEN LNGKIQENTFKQQEEISKLE ERVYNVSAEIMAMKEEQVHL EQEIKGEVKVLNNITNDLRL KDWEHSQTLRNITLIQGPPG PPGEKGDRGPTGESGPRGFP GPIGPPGLKGDRGAIGFPG |
Additional Info
| Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
| Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Macrophage Scavenger Receptor Types I And Ii proteinMacrophage Acetylated Ldl Receptor I And Ii proteinScavenger Receptor Class A Member 1 proteinCd Antigen Cd204 proteinMSR1 proteinSCARA1 protein |
Information sourced from Uniprot.org