Human MOCS2 protein (Recombinant) (N-GST & C-His) (STJP010811)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MOCS2-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MOCS2 |
| Gene ID | 4338 |
| Uniprot ID | MOC2A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val2-Gly88 |
Additional Info
| Post Translational Modifications | C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3. |
| Function | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. |
| Protein Name | Molybdopterin Synthase Sulfur Carrier SubunitMoco1-AMolybdenum Cofactor Synthesis Protein 2 Small SubunitMolybdenum Cofactor Synthesis Protein 2aMocs2aMolybdopterin-Synthase Small SubunitSulfur Carrier Protein Mocs2a |
| Database Links | Reactome: R-HSA-947581 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Molybdopterin Synthase Sulfur Carrier Subunit proteinMoco1-A proteinMolybdenum Cofactor Synthesis Protein 2 Small Subunit proteinMolybdenum Cofactor Synthesis Protein 2a proteinMocs2a proteinMolybdopterin-Synthase Small Subunit proteinSulfur Carrier Protein Mocs2a proteinMOCS2 proteinMOCO1 protein |
Information sourced from Uniprot.org