Human MOCS2 protein (Recombinant) (His-Tag) (STJP017821)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017821
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General Information

Short DescriptionRecombinant-Human MOCS2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMOCS2
Gene ID4338
Uniprot IDMOC2B_HUMAN
Accession NumberNP_004522
ImmunogenHuman
Immunogen Region1-188aa
Immunogen SequenceMRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSSL EISSSCFSLE TKLPLSPPLV EDSAFEPSRK DMDEVEEKSK DVINFTAEKL SVDEVSQLVI SPLCGAISLF VGTTRNNFEG KKVISLEYEA YLPMAENEVR KICSDIRQKW PVKHIAVFHR LGLVPVSEAS IIIAVSSAHR AASLEAVSYA IDTLKAKVPI WKKEIYEESS TWKGNKECFW ASNS

Additional Info

Tissue Specificity Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
Function Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Protein Name Molybdopterin Synthase Catalytic Subunit
Moco1-B
Molybdenum Cofactor Synthesis Protein 2 Large Subunit
Molybdenum Cofactor Synthesis Protein 2b
Mocs2b
Molybdopterin-Synthase Large Subunit
Mpt Synthase Large Subunit
Database Links Reactome: R-HSA-947581
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Molybdopterin Synthase Catalytic Subunit protein
Moco1-B protein
Molybdenum Cofactor Synthesis Protein 2 Large Subunit protein
Molybdenum Cofactor Synthesis Protein 2b protein
Mocs2b protein
Molybdopterin-Synthase Large Subunit protein
Mpt Synthase Large Subunit protein
MOCS2 protein
MCBPE protein
MOCO1 protein

Information sourced from Uniprot.org

Citations

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