Human MMRN2 (Multimerin 2) Sandwich ELISA Kit (STJE0010701)
SPECIFICATIONS
General Information
| Short Description | This MMRN2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 33pg/mL |
| Detection Limit | 78.1-5000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | MMRN2 |
| Gene ID | 79812 |
| Uniprot ID | MMRN2_HUMAN |
| Sample Type | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | Endothelium. |
| Post Translational Modifications | N- and O-glycosylated. O-fucosylated within the EMI domain (at Ser-63, Thr-67 and Thr-115) by FUT10/POFUT3 and FUT11/POFUT4. Processed by matrix metalloproteinases (MMPs) including MMP9 and, to a lesser degree, by MMP2 upon angiogenic stimulation. |
| Function | Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. |
| Protein Name | Multimerin-2Emilin-3Elastin Microfibril Interface Located Protein 3Elastin Microfibril Interfacer 3Endoglyx-1 P125/P140 Subunit |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Multimerin-2 ELISA kitEmilin-3 ELISA kitElastin Microfibril Interface Located Protein 3 ELISA kitElastin Microfibril Interfacer 3 ELISA kitEndoglyx-1 P125/P140 Subunit ELISA kitMMRN2 ELISA kitEMILIN3 ELISA kit |
| output |
Information sourced from Uniprot.org