Human MMP19 (Matrix Metalloproteinase 19) Sandwich ELISA Kit (STJE0010662)
SPECIFICATIONS
General Information
| Short Description | This MMP19 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.109ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | MMP19 |
| Gene ID | 4327 |
| Uniprot ID | MMP19_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients. |
| Post Translational Modifications | Activated by autolytic cleavage after Lys-97. Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin. |
| Protein Name | Matrix Metalloproteinase-19Mmp-19Matrix Metalloproteinase RasiMatrix Metalloproteinase-18Mmp-18 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Matrix Metalloproteinase-19 ELISA kitMmp-19 ELISA kitMatrix Metalloproteinase Rasi ELISA kitMatrix Metalloproteinase-18 ELISA kitMmp-18 ELISA kitMMP19 ELISA kitMMP18 ELISA kitRASI ELISA kit |
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Information sourced from Uniprot.org