Human MMP12 (MMP12) Antibody Pair (STJAP00785)
General Information
| Short Description | This MMP12 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R49-3R-7/R93-7T-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MMP12 |
| Gene ID | 4321 |
| Uniprot ID | MMP12_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Found in alveolar macrophages but not in peripheral blood monocytes. |
| Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
| Protein Name | Macrophage MetalloelastaseMmeMacrophage ElastaseMeHmeMatrix Metalloproteinase-12Mmp-12 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Pair Names | Macrophage Metalloelastase antibody pairMme antibody pairMacrophage Elastase antibody pairMe antibody pairHme antibody pairMatrix Metalloproteinase-12 antibody pairMmp-12 antibody pairMMP12 antibody pairHME antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MMP12 (MMP12) Antibody Pair (STJAP00785)
This antibody pair detects human MMP12 (UniProt P39900) and has confirmed reactivity against human samples only. It is intended for research use only and is not validated for other species.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL in 0.01M PBS, pH 7.2, and purified by affinity chromatography. The clone IDs are R49-3R-7 and R93-7T-5 respectively.
This pair has been validated for use in ELISA. No other assay formats are listed as validated for this product.
Working concentrations are determined by the end user and are not predefined in the product specifications. It is recommended to perform a titration experiment to establish optimal concentrations for your specific assay conditions.
Both components should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.