Human MMP1 (MMP1) Antibody Pair (STJAP00782)
General Information
| Short Description | This MMP1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R87-8B-9/R71-4W-3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MMP1 |
| Gene ID | 4312 |
| Uniprot ID | MMP1_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | Undergoes autolytic cleavage to two major forms (22 kDa and 27 kDa). A minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase. Tyrosine phosphorylated in platelets by PKDCC/VLK. |
| Function | Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. |
| Protein Name | Interstitial CollagenaseFibroblast CollagenaseMatrix Metalloproteinase-1Mmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-210991Reactome: R-HSA-381426Reactome: R-HSA-6785807 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Pair Names | Interstitial Collagenase antibody pairFibroblast Collagenase antibody pairMatrix Metalloproteinase-1 antibody pairMmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase antibody pairMMP1 antibody pairCLG antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MMP1 (MMP1) Antibody Pair (STJAP00782)
This antibody pair is designed to detect human MMP1 (Matrix Metalloproteinase 1, UniProt P03956). Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs (clone IDs R87-8B-9 and R71-4W-3), supplied unconjugated at 1 mg/mL in 0.01M PBS pH 7.2. Both have been affinity purified.
This pair is validated for use in ELISA. The working dilution for each antibody is determined by the end user and should be optimized for the specific assay configuration.
Both antibodies are supplied unconjugated, so the end user is responsible for any labeling or conjugation required for detection in a sandwich ELISA format.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, avoiding repeated freeze/thaw cycles.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.