Human MMP-9 (Matrix Metalloproteinase-9) Antibody Pair (STJAP00050)
General Information
| Short Description | This MMP-9 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP9 |
| Gene ID | 4318 |
| Uniprot ID | MMP9_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human MMP-9 protein.Detection Immunogen: Recombinant Human MMP-9 protein. |
Additional Info
| Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
| Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
| Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
| Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-2022090Reactome: R-HSA-3928665Reactome: R-HSA-6785807Reactome: R-HSA-6798695Reactome: R-HSA-9009391 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Pair Names | Matrix Metalloproteinase-9 antibody pairMmp-9 antibody pair92 Kda Gelatinase antibody pair92 Kda Type Iv Collagenase antibody pairGelatinase B antibody pairGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 antibody pairMMP9 antibody pairCLG4B antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MMP-9 (Matrix Metalloproteinase-9) Antibody Pair (STJAP00050)
This antibody pair detects human MMP-9 (Matrix Metalloproteinase-9, UniProt P14780) and is validated for use with human samples only. No cross-reactivity data for other species is provided.
This antibody pair is validated for ELISA only. No other assay formats are listed for this product.
The capture antibody is an unconjugated mouse monoclonal antibody supplied at 0.5 mg/mL, purified by Protein A or G. The detection antibody is a biotin-conjugated goat polyclonal antibody supplied at 0.5 mg/mL, purified by antigen affinity. Both components are formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
Both the capture and detection antibodies were raised against recombinant human MMP-9 protein. No specific immunogen region is specified for either component.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to preserve antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.